Professor Lack's patient-centred approach combines scientific rigour with deep empathy for patients and families managing allergies. His research, particularly the landmark LEAP Study, proved that early introduction of foods can prevent allergies – findings that have transformed global health guidelines and helped thousands of children worldwide.

He has developed the Dual Allergen Exposure Hypothesis, which revealed how disrupted skin barriers in infants can lead to food allergies. This discovery led to the landmark LEAP study, showing that introducing peanuts early to high-risk infants reduces their chance of developing peanut allergies by over 80% - findings that have reshaped global prevention guidelines. The subsequent EAT study extended these findings to other common allergens like eggs, marking a fundamental shift in how we approach allergy prevention.

Professor Lack has also advanced allergy diagnosis through innovative tools like the Basophil Activation Test, enabling more precise and reliable results. His contributions to allergy science have earned international recognition, including the prestigious David Sackett Award for Clinical Trial of the Year.